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Accelerated aging in normal breast tissue of women with breast cancer

BACKGROUND: DNA methylation alterations have similar patterns in normal aging tissue and in cancer. In this study, we investigated breast tissue-specific age-related DNA methylation alterations and used those methylation sites to identify individuals with outlier phenotypes. Outlier phenotype is ide...

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Detalles Bibliográficos
Autores principales: Panjarian, Shoghag, Madzo, Jozef, Keith, Kelsey, Slater, Carolyn M., Sapienza, Carmen, Jelinek, Jaroslav, Issa, Jean-Pierre J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140515/
https://www.ncbi.nlm.nih.gov/pubmed/34022936
http://dx.doi.org/10.1186/s13058-021-01434-7