Chemical synthesis of peptidoglycan mimetic–disaccharide-tetrapeptide conjugate and its hydrolysis by bacteriophage T5, RB43 and RB49 L-alanyl-D-glutamate peptidases

BACKGROUND: Endolysins of a number of bacteriophages, including coliphages T5, RB43, and RB49, target the peptidoglycans of the bacterial cell wall. The backbone of these bacterial peptidoglycans consist of alternating N-acetylglucosamine and N-acetylmuramic acid residues that is further “reinforced...

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Detalles Bibliográficos
Autores principales: Azev, Viatcheslav, Chulin, Alexey, Molchanov, Maxim, Prokhorov, Dmitry, Mikoulinskaia, Galina, Uversky, Vladimir N., Kutyshenko, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140593/
https://www.ncbi.nlm.nih.gov/pubmed/34055493
http://dx.doi.org/10.7717/peerj.11480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140593/
https://www.ncbi.nlm.nih.gov/pubmed/34055493
http://dx.doi.org/10.7717/peerj.11480

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