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Assessing the functional relevance of splice isoforms

Alternative splicing of messenger RNA can generate an array of mature transcripts, but it is not clear how many go on to produce functionally relevant protein isoforms. There is only limited evidence for alternative proteins in proteomics analyses and data from population genetic variation studies i...

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Detalles Bibliográficos
Autores principales: Pozo, Fernando, Martinez-Gomez, Laura, Walsh, Thomas A, Rodriguez, José Manuel, Di Domenico, Tomas, Abascal, Federico, Vazquez, Jesús, Tress, Michael L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140736/
https://www.ncbi.nlm.nih.gov/pubmed/34046593
http://dx.doi.org/10.1093/nargab/lqab044