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Building External Control Arms From Patient-Level Electronic Health Record Data to Replicate the Randomized IMblaze370 Control Arm in Metastatic Colorectal Cancer

External control (EC) arms derived from electronic health records (EHRs) can provide appropriate comparison groups when randomized control arms are not feasible, but have not been explored for metastatic colorectal cancer (mCRC) trials. We constructed EC arms from two patient-level EHR-derived datab...

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Detalles Bibliográficos
Autores principales: Schröder, Carsten, Lawrance, Marcus, Li, Chen, Lenain, Christelle, Mhatre, Shivani K., Fakih, Marwan, Reyes-Rivera, Irmarie, Bretscher, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140779/
https://www.ncbi.nlm.nih.gov/pubmed/33891473
http://dx.doi.org/10.1200/CCI.20.00149