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NTRK Fusions Identified in Pediatric Tumors: The Frequency, Fusion Partners, and Clinical Outcome

Neurotrophic tyrosine receptor kinase (NTRK) fusions have been described as oncogenic drivers in a variety of tumors. However, little is known about the overall frequency of NTRK fusion in unselected pediatric tumors. Here, we assessed the frequency, fusion partners, and clinical course in pediatric...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaonan, Kotch, Chelsea, Fox, Elizabeth, Surrey, Lea F., Wertheim, Gerald B., Baloch, Zubair W., Lin, Fumin, Pillai, Vinodh, Luo, Minjie, Kreiger, Portia A., Pogoriler, Jennifer E., Linn, Rebecca L., Russo, Pierre A., Santi, Mariarita, Resnick, Adam C., Storm, Phillip B., Hunger, Stephen P., Bauer, Andrew J., Li, Marilyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140782/
https://www.ncbi.nlm.nih.gov/pubmed/34036219
http://dx.doi.org/10.1200/PO.20.00250