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Canagliflozin Facilitates Reverse Cholesterol Transport Through Activation of AMPK/ABC Transporter Pathway

BACKGROUND AND PURPOSE: Cholesterol is an essential lipid and its homeostasis is a major factor for many diseases, such as hyperlipidemia, atherosclerosis, diabetes, and obesity. Sodium-glucose cotransporter 2 (SGLT2) inhibitor canagliflozin (Cana) is a new kind of hypoglycemic agent, which decrease...

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Detalles Bibliográficos
Autores principales: Zhao, Yingnan, Li, Yanping, Liu, Qinhui, Tang, Qin, Zhang, Zijing, Zhang, Jinhang, Huang, Cuiyuan, Huang, Hui, Zhang, Guorong, Zhou, Jian, Yan, Jiamin, Xia, Yan, Zhang, Zhiyong, He, Jinhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140894/
https://www.ncbi.nlm.nih.gov/pubmed/34040350
http://dx.doi.org/10.2147/DDDT.S306367