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Electronic structure and reactivity of tirapazamine as a radiosensitizer

Tirapazamine (TP) has been shown to enhance the cytotoxic effects of ionizing radiation in hypoxic cells, thus making it a candidate for a radiosensitizer. This selective behavior is often directly linked to the abundance of O(2). In this paper, we study the electronic properties of TP in vacuum, mi...

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Detalles Bibliográficos
Autores principales: Romero, José, Maihom, Thana, Limão-Vieira, Paulo, Probst, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140980/
https://www.ncbi.nlm.nih.gov/pubmed/34021836
http://dx.doi.org/10.1007/s00894-021-04771-8