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Electronic structure and reactivity of tirapazamine as a radiosensitizer
Tirapazamine (TP) has been shown to enhance the cytotoxic effects of ionizing radiation in hypoxic cells, thus making it a candidate for a radiosensitizer. This selective behavior is often directly linked to the abundance of O(2). In this paper, we study the electronic properties of TP in vacuum, mi...
Autores principales: | Romero, José, Maihom, Thana, Limão-Vieira, Paulo, Probst, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140980/ https://www.ncbi.nlm.nih.gov/pubmed/34021836 http://dx.doi.org/10.1007/s00894-021-04771-8 |
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