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p63 suppresses the ability of pregnancy-identified mammary epithelial cells (PIMECs) to drive HER2-positive breast cancer

While pregnancy is known to reduce a woman’s life-long risk of breast cancer, clinical data suggest that it can specifically promote HER2 (human EGF receptor 2)-positive breast cancer subtype (HER2+ BC). HER2+ BC, characterized by amplification of HER2, comprises about 20% of all sporadic breast can...

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Detalles Bibliográficos
Autores principales: Eyermann, Christopher E., Li, Jinyu, Alexandrova, Evguenia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141055/
https://www.ncbi.nlm.nih.gov/pubmed/34023861
http://dx.doi.org/10.1038/s41419-021-03795-5