Repression of Polyol Pathway Activity by Hemidesmus indicus var. pubescens R.Br. Linn Root Extract, an Aldose Reductase Inhibitor: An In Silico and Ex Vivo Study

ABSTRACT: Development of diabetic cataract is mainly associated with the accumulation of sorbitol via the polyol pathway through the action of Aldose reductase (AR). Hence, AR inhibitors are considered as potential agents in the management of diabetic cataract. This study explored the AR inhibition...

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Detalles Bibliográficos
Autores principales: Haroon, Hajira Banu, Perumalsamy, Vijaybhanu, Nair, Gouri, Anand, Dhanusha Koppal, Kolli, Rajitha, Monichen, Joel, Prabha, Kanchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141070/
https://www.ncbi.nlm.nih.gov/pubmed/33284412
http://dx.doi.org/10.1007/s13659-020-00290-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141070/
https://www.ncbi.nlm.nih.gov/pubmed/33284412
http://dx.doi.org/10.1007/s13659-020-00290-w

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