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Computational Design of Novel Allosteric Inhibitors for Plasmodium falciparum DegP

The serine protease, DegP exhibits proteolytic and chaperone activities, essential for cellular protein quality control and normal cell development in eukaryotes. The P. falciparum DegP is essential for the parasite survival and required to combat the oscillating thermal stress conditions during the...

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Detalles Bibliográficos
Autores principales: Shehzad, Sadaf, Pandey, Rajan, Malhotra, Pawan, Gupta, Dinesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141111/
https://www.ncbi.nlm.nih.gov/pubmed/34066964
http://dx.doi.org/10.3390/molecules26092742