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Immersion in Raloxifene does not significantly improve bone toughness or screw pull-out strength in multiple in vitro models

BACKGROUND: Failure of surgical fixation in orthopaedic fractures occurs at a significantly higher rate in osteoporotic patients due to weakened osteoporotic bone. A therapy to acutely improve the mechanical properties of bone during fracture repair would have profound clinical impact. A previous st...

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Detalles Bibliográficos
Autores principales: Eby, Michael R., Cristino, Danielle M., Counihan, Matthew, Masada, Kendall M., Ahn, Jaimo, Hast, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141119/
https://www.ncbi.nlm.nih.gov/pubmed/34022860
http://dx.doi.org/10.1186/s12891-021-04342-1