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The effects of a mitochondrial targeted peptide (elamipretide/SS31) on BAX recruitment and activation during apoptosis

OBJECTIVE: Elamipretide (SS31) is a mitochondria-targeted peptide that has reported functions of stabilizing mitochondrial cristae structure and improving mitochondrial bioenergetics. Several studies have documented cell protective features of this peptide, including impairment of intrinsic apoptosi...

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Detalles Bibliográficos
Autores principales: Grosser, Joshua A., Fehrman, Rachel L., Keefe, Dennis, Redmon, Martin, Nickells, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141144/
https://www.ncbi.nlm.nih.gov/pubmed/34022923
http://dx.doi.org/10.1186/s13104-021-05613-9