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The effects of a mitochondrial targeted peptide (elamipretide/SS31) on BAX recruitment and activation during apoptosis
OBJECTIVE: Elamipretide (SS31) is a mitochondria-targeted peptide that has reported functions of stabilizing mitochondrial cristae structure and improving mitochondrial bioenergetics. Several studies have documented cell protective features of this peptide, including impairment of intrinsic apoptosi...
Autores principales: | Grosser, Joshua A., Fehrman, Rachel L., Keefe, Dennis, Redmon, Martin, Nickells, Robert W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141144/ https://www.ncbi.nlm.nih.gov/pubmed/34022923 http://dx.doi.org/10.1186/s13104-021-05613-9 |
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