Selective DNA Demethylation Accompanies T Cell Homeostatic Proliferation and Gene Regulation in Lupus-Prone lpr Mice

Systemic lupus erythematosus (SLE) is characterized by increased DNA demethylation in T cells, although it is unclear whether this occurs primarily in a subset of SLE T cells. The process driving the DNA demethylation and the consequences on overall gene expression are also poorly understood and whe...

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Detalles Bibliográficos
Autores principales: Scharer, Christopher D., Fortner, Karen A., Dragon, Julie A., Tighe, Scott, Boss, Jeremy M., Budd, Ralph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141279/
https://www.ncbi.nlm.nih.gov/pubmed/33097564
http://dx.doi.org/10.4049/immunohorizons.2000078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141279/
https://www.ncbi.nlm.nih.gov/pubmed/33097564
http://dx.doi.org/10.4049/immunohorizons.2000078

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