Suppressor of cytokine signalling 3 (SOCS3) expressed in podocytes attenuates glomerulonephritis and suppresses autoantibody production in an imiquimod-induced lupus model

OBJECTIVE: Recently, podocytes have been recognised not only as a physical barrier to prevent urinary protein loss but also as producers of proinflammatory cytokines. However, the roles of podocytes in the pathogenesis of lupus nephritis (LN) remain largely unknown. This study aims to determine the...

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Detalles Bibliográficos
Autores principales: Fukuta, Masashi, Suzuki, Kotaro, Kojima, Shotaro, Yabe, Yoko, Suzuki, Kazumasa, Iida, Kazuma, Yamada, Hiroyuki, Makino, Shinichi, Iwata, Arifumi, Tanaka, Shigeru, Iwamoto, Taro, Suto, Akira, Nakagomi, Daiki, Wakashin, Hidefumi, Maezawa, Yuko, Maezawa, Yoshiro, Takemoto, Minoru, Asanuma, Katsuhiko, Nakajima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Animal Models
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141454/
https://www.ncbi.nlm.nih.gov/pubmed/34016718
http://dx.doi.org/10.1136/lupus-2020-000426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141454/
https://www.ncbi.nlm.nih.gov/pubmed/34016718
http://dx.doi.org/10.1136/lupus-2020-000426

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