Recognition of a tandem lesion by DNA bacterial formamidopyrimidine glycosylases explored combining molecular dynamics and machine learning

The combination of several closely spaced DNA lesions, which can be induced by a single radical hit, constitutes a hallmark in the DNA damage landscape and radiation chemistry. The occurrence of such a tandem base lesion gives rise to a strong coupling with the double helix degrees of freedom and in...

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Detalles Bibliográficos
Autores principales: Bignon, Emmanuelle, Gillet, Natacha, Chan, Chen-Hui, Jiang, Tao, Monari, Antonio, Dumont, Elise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141532/
https://www.ncbi.nlm.nih.gov/pubmed/34093997
http://dx.doi.org/10.1016/j.csbj.2021.04.055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141532/
https://www.ncbi.nlm.nih.gov/pubmed/34093997
http://dx.doi.org/10.1016/j.csbj.2021.04.055

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