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Design of novel peptide inhibitors against the conserved bacterial transcription terminator, Rho
The transcription terminator Rho regulates many physiological processes in bacteria, such as antibiotic sensitivity, DNA repair, RNA remodeling, and so forth, and hence, is a potential antimicrobial target, which is unexplored. The bacteriophage P4 capsid protein, Psu, moonlights as a natural Rho an...
Autores principales: | Ghosh, Gairika, Sharma, Pankaj V., Kumar, Amit, Jain, Sriyans, Sen, Ranjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141534/ https://www.ncbi.nlm.nih.gov/pubmed/33845047 http://dx.doi.org/10.1016/j.jbc.2021.100653 |
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