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Activation of Invariant Natural Killer T Cells by α-Galactosylceramide Attenuates the Development of Angiotensin II-Mediated Abdominal Aortic Aneurysm in Obese ob/ob Mice

The infiltration and activation of macrophages as well as lymphocytes within the aorta contribute to the pathogenesis of abdominal aortic aneurysm (AAA). Invariant natural killer T (iNKT) cells are unique subset of T lymphocytes and have a crucial role in atherogenesis. However, it remains unclear w...

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Detalles Bibliográficos
Autores principales: Saito, Akimichi, Ishimori, Naoki, Tokuhara, Satoshi, Homma, Tsuneaki, Nishikawa, Mikito, Iwabuchi, Kazuya, Tsutsui, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141584/
https://www.ncbi.nlm.nih.gov/pubmed/34041282
http://dx.doi.org/10.3389/fcvm.2021.659418