Rheb-mTOR activation rescues Aβ-induced cognitive impairment and memory function by restoring miR-146 activity in glial cells

Deposition of amyloid beta plaques in adult rat or human brain is associated with increased production of proinflammatory cytokines by associated glial cells that are responsible for degeneration of the diseased tissue. The expression of these cytokines is usually under check and is controlled at th...

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Detalles Bibliográficos
Autores principales: De, Dipayan, Mukherjee, Ishita, Guha, Subhalakshmi, Paidi, Ramesh Kumar, Chakrabarti, Saikat, Biswas, Subhas C., Bhattacharyya, Suvendra N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141608/
https://www.ncbi.nlm.nih.gov/pubmed/34094708
http://dx.doi.org/10.1016/j.omtn.2021.04.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141608/
https://www.ncbi.nlm.nih.gov/pubmed/34094708
http://dx.doi.org/10.1016/j.omtn.2021.04.008

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