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Fat-Secreted Ceramides Regulate Vascular Redox State and Influence Outcomes in Patients With Cardiovascular Disease

BACKGROUND: Obesity is associated with increased cardiovascular risk; however, the potential role of dysregulations in the adipose tissue (AT) metabolome is unknown. OBJECTIVES: The aim of this study was to explore the role of dysregulation in the AT metabolome on vascular redox signaling and cardio...

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Detalles Bibliográficos
Autores principales: Akawi, Nadia, Checa, Antonio, Antonopoulos, Alexios S., Akoumianakis, Ioannis, Daskalaki, Evangelia, Kotanidis, Christos P., Kondo, Hidekazu, Lee, Kirsten, Yesilyurt, Dilan, Badi, Ileana, Polkinghorne, Murray, Akbar, Naveed, Lundgren, Julie, Chuaiphichai, Surawee, Choudhury, Robin, Neubauer, Stefan, Channon, Keith M., Torekov, Signe S., Wheelock, Craig E., Antoniades, Charalambos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Biomedical 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141611/
https://www.ncbi.nlm.nih.gov/pubmed/34016263
http://dx.doi.org/10.1016/j.jacc.2021.03.314