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Cancer-derived exosome miRNAs induce skeletal muscle wasting by Bcl-2-mediated apoptosis in colon cancer cachexia

Cancer cachexia is a kind of whole-body metabolic disorder syndrome accompanied by severe wasting of muscle tissue in which cancer exosomes may be involved. Analysis of clinical samples showed that the serum exosome concentrations were correlated with the development of cancer cachexia. Exosomes sec...

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Detalles Bibliográficos
Autores principales: Miao, Chunxiao, Zhang, Wanli, Feng, Lixing, Gu, Xiaofan, Shen, Qiang, Lu, Shanshan, Fan, Meng, Li, Yiwei, Guo, Xianling, Ma, Yushui, Liu, Xuan, Wang, Hui, Zhang, Xiongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141664/
https://www.ncbi.nlm.nih.gov/pubmed/34094711
http://dx.doi.org/10.1016/j.omtn.2021.04.015