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Yin and Yang in Post-Translational Modifications of Human D-Amino Acid Oxidase

In the central nervous system, the flavoprotein D-amino acid oxidase is responsible for catabolizing D-serine, the main endogenous coagonist of N-methyl-D-aspartate receptor. Dysregulation of D-serine brain levels in humans has been associated with neurodegenerative and psychiatric disorders. This D...

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Detalles Bibliográficos
Autores principales: Sacchi, Silvia, Rabattoni, Valentina, Miceli, Matteo, Pollegioni, Loredano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141710/
https://www.ncbi.nlm.nih.gov/pubmed/34041270
http://dx.doi.org/10.3389/fmolb.2021.684934