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Structural diversity of the coenzyme methylofuran and identification of enzymes for the biosynthesis of its polyglutamate side chain
Methylofuran (MYFR) is a formyl-carrying coenzyme essential for the oxidation of formaldehyde in most methylotrophic bacteria. In Methylorubrum extorquens, MYFR contains a large and branched polyglutamate side chain of up to 24 glutamates. These glutamates play an essential role in interfacing the c...
Autores principales: | Hemmann, Jethro L., Brühwiler, Manuel R., Bortfeld-Miller, Miriam, Vorholt, Julia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141765/ https://www.ncbi.nlm.nih.gov/pubmed/33894199 http://dx.doi.org/10.1016/j.jbc.2021.100682 |
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