Oxidation of peroxiredoxin-4 induces oligomerization and promotes interaction with proteins governing protein folding and endoplasmic reticulum stress

Peroxiredoxins (PRDXs) catalyze the reduction of hydrogen peroxide (H(2)O(2)). PRDX4 is the only peroxiredoxin located within the endoplasmic reticulum (ER) and is the most highly expressed H(2)O(2) scavenger in the ER. PRDX4 has emerged as an important player in numerous diseases, such as fibrosis...

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Detalles Bibliográficos
Autores principales: Elko, Evan A., Manuel, Allison M., White, Sheryl, Zito, Ester, van der Vliet, Albert, Anathy, Vikas, Janssen-Heininger, Yvonne M.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141880/
https://www.ncbi.nlm.nih.gov/pubmed/33895140
http://dx.doi.org/10.1016/j.jbc.2021.100665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141880/
https://www.ncbi.nlm.nih.gov/pubmed/33895140
http://dx.doi.org/10.1016/j.jbc.2021.100665

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