Sp1 is a substrate of Keap1 and regulates the activity of CRL4A(WDR23) ubiquitin ligase toward Nrf2

Nuclear factor erythroid 2–related factor 2 (Nrf2) is a critical transcription factor that orchestrates cellular responses to oxidative stress. Because the dysregulation of Nrf2 has been implicated in many diseases, precise regulation of its protein level is crucial for maintaining homeostasis. Kelc...

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Detalles Bibliográficos
Autores principales: Siswanto, Ferbian Milas, Oguro, Ami, Imaoka, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141886/
https://www.ncbi.nlm.nih.gov/pubmed/33895141
http://dx.doi.org/10.1016/j.jbc.2021.100704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141886/
https://www.ncbi.nlm.nih.gov/pubmed/33895141
http://dx.doi.org/10.1016/j.jbc.2021.100704

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