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The α3 subunit of GABA(A) receptors promotes formation of inhibitory synapses in the absence of collybistin
Signaling at nerve cell synapses is a key determinant of proper brain function, and synaptic defects—or synaptopathies—are at the basis of many neurological and psychiatric disorders. Collybistin (CB), a brain-specific guanine nucleotide exchange factor, is essential for the formation of γ-aminobuty...
Autores principales: | Wagner, Sven, Lee, ChoongKu, Rojas, Lucia, Specht, Christian G., Rhee, JeongSeop, Brose, Nils, Papadopoulos, Theofilos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8141935/ https://www.ncbi.nlm.nih.gov/pubmed/33901490 http://dx.doi.org/10.1016/j.jbc.2021.100709 |
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