Losartan protects against osteoarthritis by repressing the TGF-β1 signaling pathway via upregulation of PPARγ

OBJECTIVE: Losartan and activation of the peroxisome proliferator-activated receptor-γ (PPARγ) have been previously reported to alleviate the progression of osteoarthritis (OA). However, the nature of the interaction between losartan and PPARγ in OA remains elusive. Therefore, we aimed to investigat...

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Detalles Bibliográficos
Autores principales: Deng, Zhenhan, Chen, Fei, Liu, Yuwei, Wang, Jinping, Lu, Wei, Jiang, Wei, Zhu, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142050/
https://www.ncbi.nlm.nih.gov/pubmed/34094856
http://dx.doi.org/10.1016/j.jot.2021.03.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142050/
https://www.ncbi.nlm.nih.gov/pubmed/34094856
http://dx.doi.org/10.1016/j.jot.2021.03.005

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