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Losartan protects against osteoarthritis by repressing the TGF-β1 signaling pathway via upregulation of PPARγ
OBJECTIVE: Losartan and activation of the peroxisome proliferator-activated receptor-γ (PPARγ) have been previously reported to alleviate the progression of osteoarthritis (OA). However, the nature of the interaction between losartan and PPARγ in OA remains elusive. Therefore, we aimed to investigat...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Chinese Speaking Orthopaedic Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142050/ https://www.ncbi.nlm.nih.gov/pubmed/34094856 http://dx.doi.org/10.1016/j.jot.2021.03.005 |