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The mycobacterial proteasomal ATPase Mpa forms a gapped ring to engage the 20S proteasome

Although many bacterial species do not possess proteasome systems, the actinobacteria, including the human pathogen Mycobacterium tuberculosis, use proteasome systems for targeted protein removal. Previous structural analyses of the mycobacterial proteasome ATPase Mpa revealed a general structural c...

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Detalles Bibliográficos
Autores principales: Yin, Yanting, Kovach, Amanda, Hsu, Hao-Chi, Darwin, K. Heran, Li, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142254/
https://www.ncbi.nlm.nih.gov/pubmed/33930464
http://dx.doi.org/10.1016/j.jbc.2021.100713