Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway

Autophagy is a degradative pathway required to maintain homeostasis. Neuronal autophagosomes form constitutively at the axon terminal and mature via lysosomal fusion during dynein-mediated transport to the soma. How the dynein–autophagosome interaction is regulated is unknown. Here, we identify mult...

Descripción completa

Detalles Bibliográficos
Autores principales: Cason, Sydney E., Carman, Peter J., Van Duyne, Claire, Goldsmith, Juliet, Dominguez, Roberto, Holzbaur, Erika L.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142281/
https://www.ncbi.nlm.nih.gov/pubmed/34014261
http://dx.doi.org/10.1083/jcb.202010179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142281/
https://www.ncbi.nlm.nih.gov/pubmed/34014261
http://dx.doi.org/10.1083/jcb.202010179

Ejemplares similares