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Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway
Autophagy is a degradative pathway required to maintain homeostasis. Neuronal autophagosomes form constitutively at the axon terminal and mature via lysosomal fusion during dynein-mediated transport to the soma. How the dynein–autophagosome interaction is regulated is unknown. Here, we identify mult...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142281/ https://www.ncbi.nlm.nih.gov/pubmed/34014261 http://dx.doi.org/10.1083/jcb.202010179 |