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Racemases and epimerases operating through a 1,1-proton transfer mechanism: reactivity, mechanism and inhibition

Racemases and epimerases catalyse changes in the stereochemical configurations of chiral centres and are of interest as model enzymes and as biotechnological tools. They also occupy pivotal positions within metabolic pathways and, hence, many of them are important drug targets. This review summarise...

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Detalles Bibliográficos
Autores principales: Lloyd, Matthew D., Yevglevskis, Maksims, Nathubhai, Amit, James, Tony D., Threadgill, Michael D., Woodman, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142540/
https://www.ncbi.nlm.nih.gov/pubmed/34027955
http://dx.doi.org/10.1039/d0cs00540a