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Racemases and epimerases operating through a 1,1-proton transfer mechanism: reactivity, mechanism and inhibition
Racemases and epimerases catalyse changes in the stereochemical configurations of chiral centres and are of interest as model enzymes and as biotechnological tools. They also occupy pivotal positions within metabolic pathways and, hence, many of them are important drug targets. This review summarise...
Autores principales: | Lloyd, Matthew D., Yevglevskis, Maksims, Nathubhai, Amit, James, Tony D., Threadgill, Michael D., Woodman, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142540/ https://www.ncbi.nlm.nih.gov/pubmed/34027955 http://dx.doi.org/10.1039/d0cs00540a |
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