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Inhibition of Retinal Ganglion Cell Loss By a Novel ROCK Inhibitor (E212) in Ischemic Optic Nerve Injury Via Antioxidative and Anti-Inflammatory Actions
PURPOSE: This study investigated the neuroprotective effects of administration of ROCK inhibitor E212 on ischemic optic neuropathy. METHODS: Rats received an intravitreal injection of either E212 or PBS immediately after optic nerve infarct. The oxidative stress in the retina was detected by perform...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142697/ https://www.ncbi.nlm.nih.gov/pubmed/34015079 http://dx.doi.org/10.1167/iovs.62.6.21 |