Pretreatment with Propofol Reduces Pulmonary Injury in a Pig Model of Intestinal Ischemia-Reperfusion via Suppressing the High-Mobility Group Box 1 Protein (HMGB1)/Toll-Like Receptor 4 (TLR4)/Protein Kinase R (PKR) Signaling Pathway

BACKGROUND: Propofol improves rodent pulmonary injury after intestinal ischemia-reperfusion (IIR). However, its effect and underlying mechanisms in large animals remain unclear. Here, we examined whether pretreatment with propofol could relieve lung injury during IIR in pigs, then investigated the u...

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Detalles Bibliográficos
Autores principales: Bian, Wen-yu, Chen, Ya-ping, Xu, Bo, Tang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142706/
https://www.ncbi.nlm.nih.gov/pubmed/34010266
http://dx.doi.org/10.12659/MSM.930478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142706/
https://www.ncbi.nlm.nih.gov/pubmed/34010266
http://dx.doi.org/10.12659/MSM.930478

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