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Toxicity Threshold of Perfluorocarbon Liquids for Intraocular Use: Dose–Response Assessment of In Vitro Cytotoxicity of Possible Contaminants

PURPOSE: This study assessed the cytotoxicity of the impurities detected in the perfluorooctane (PFO) batches for vitreoretinal surgery that were associated with serious adverse incidents of ocular toxicity, namely, the perfluorooctanoic acid (PFOA), 1H,1H,7H-dodecafluoro-1-heptanol (DFH), 1H-perflu...

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Detalles Bibliográficos
Autores principales: Romano, Mario Rosario, Gatto, Claudio, Giurgola, Laura, Ragazzi, Eugenio, D'Amato Tóthová, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142790/
https://www.ncbi.nlm.nih.gov/pubmed/34111270
http://dx.doi.org/10.1167/tvst.10.6.24