Proof of Concept: Drug Selection? Or Dose Selection? Thoughts on Multiplicity Issues

In new drug development process, one of the most important milestones for a drug candidate is to establish Proof of Concept (PoC) at early Phase II stage. Among many challenges in PoC clinical trial design and analysis, the application of multiplicity comparison procedures (MCP) is frequently discus...

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Detalles Bibliográficos
Autores principales: Li, Qian H., Deng, Qiqi, Ting, Naitee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142878/
https://www.ncbi.nlm.nih.gov/pubmed/34028669
http://dx.doi.org/10.1007/s43441-021-00299-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142878/
https://www.ncbi.nlm.nih.gov/pubmed/34028669
http://dx.doi.org/10.1007/s43441-021-00299-4

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