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Loss of KCNQ2 or KCNQ3 Leads to Multifocal Time-Varying Activity in the Neonatal Forebrain Ex Vivo

Epileptic encephalopathies represent a group of disorders often characterized by refractory seizures, regression in cognitive development, and typically poor prognosis. Dysfunction of KCNQ2 and KCNQ3 channels has emerged as a major cause of neonatal epilepsy. However, our understanding of the cellul...

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Detalles Bibliográficos
Autores principales: Hou, Bowen, Varghese, Nissi, Soh, Heun, Santaniello, Sabato, Tzingounis, Anastasios V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143017/
https://www.ncbi.nlm.nih.gov/pubmed/33863780
http://dx.doi.org/10.1523/ENEURO.0024-21.2021