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The Interaction Analysis of SNP Variants and DNA Methylation Identifies Novel Methylated Pathogenesis Genes in Congenital Heart Diseases

Congenital heart defect (CHD) is a rare and complicated disease with a high mortality rate. Its etiology remains unclear and includes many aspects. DNA methylation has been indicated to be involved in heart development in the early stage of life, and aberrant methylation level was related to CHDs. T...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Ma, Xiaoqin, Zhang, Qi, Chen, Yinghui, Wu, Dan, Zhao, Pengjun, Yu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143053/
https://www.ncbi.nlm.nih.gov/pubmed/34041244
http://dx.doi.org/10.3389/fcell.2021.665514