Effective Activation of BK(Ca) Channels by QO-40 (5-(Chloromethyl)-3-(Naphthalen-1-yl)-2-(Trifluoromethyl)Pyrazolo [1,5-a]pyrimidin-7(4H)-one), Known to Be an Opener of KCNQ2/Q3 Channels

QO-40 (5-(chloromethyl)-3-(naphthalene-1-yl)-2-(trifluoromethyl) pyrazolo[1,5-a]pyrimidin-7(4H)-one) is a novel and selective activator of KCNQ2/KCNQ3 K(+) channels. However, it remains largely unknown whether this compound can modify any other type of plasmalemmal ionic channel. The effects of QO-4...

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Detalles Bibliográficos
Autores principales: Chang, Wei-Ting, Wu, Sheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143083/
https://www.ncbi.nlm.nih.gov/pubmed/33919092
http://dx.doi.org/10.3390/ph14050388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143083/
https://www.ncbi.nlm.nih.gov/pubmed/33919092
http://dx.doi.org/10.3390/ph14050388

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