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Identification and Characterization of Alternatively Spliced Transcript Isoforms of IRX4 in Prostate Cancer

Alternative splicing (AS) is tightly regulated to maintain genomic stability in humans. However, tumor growth, metastasis and therapy resistance benefit from aberrant RNA splicing. Iroquois-class homeodomain protein 4 (IRX4) is a TALE homeobox transcription factor which has been implicated in prosta...

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Detalles Bibliográficos
Autores principales: Fernando, Achala, Liyanage, Chamikara, Moradi, Afshin, Janaththani, Panchadsaram, Batra, Jyotsna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143155/
https://www.ncbi.nlm.nih.gov/pubmed/33919200
http://dx.doi.org/10.3390/genes12050615