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ATG13 dynamics in nonselective autophagy and mitophagy: insights from live imaging studies and mathematical modeling

During macroautophagy/autophagy, the ULK complex nucleates autophagic precursors, which give rise to autophagosomes. We analyzed, by live imaging and mathematical modeling, the translocation of ATG13 (part of the ULK complex) to the autophagic puncta in starvation-induced autophagy and ivermectin-in...

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Detalles Bibliográficos
Autores principales: Dalle Pezze, Piero, Karanasios, Eleftherios, Kandia, Varvara, Manifava, Maria, Walker, Simon A., Gambardella Le Novère, Nicolas, Ktistakis, Nicholas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143212/
https://www.ncbi.nlm.nih.gov/pubmed/32320309
http://dx.doi.org/10.1080/15548627.2020.1749401