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ATG13 dynamics in nonselective autophagy and mitophagy: insights from live imaging studies and mathematical modeling
During macroautophagy/autophagy, the ULK complex nucleates autophagic precursors, which give rise to autophagosomes. We analyzed, by live imaging and mathematical modeling, the translocation of ATG13 (part of the ULK complex) to the autophagic puncta in starvation-induced autophagy and ivermectin-in...
Autores principales: | Dalle Pezze, Piero, Karanasios, Eleftherios, Kandia, Varvara, Manifava, Maria, Walker, Simon A., Gambardella Le Novère, Nicolas, Ktistakis, Nicholas T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143212/ https://www.ncbi.nlm.nih.gov/pubmed/32320309 http://dx.doi.org/10.1080/15548627.2020.1749401 |
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