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Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels

Epigenetic architecture is influenced by genetic and environmental factors, but little is known about their relative contributions or longitudinal dynamics. Here, we studied DNA methylation (DNAm) at over 750,000 CpG sites in mononuclear blood cells collected at birth and age 7 from 196 children of...

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Detalles Bibliográficos
Autores principales: McKennan, Chris, Naughton, Katherine, Stanhope, Catherine, Kattan, Meyer, O’Connor, George T., Sandel, Megan T., Visness, Cynthia M., Wood, Robert A., Bacharier, Leonard B., Beigelman, Avraham, Lovinsky-Desir, Stephanie, Togias, Alkis, Gern, James E., Nicolae, Dan, Ober, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143220/
https://www.ncbi.nlm.nih.gov/pubmed/32997571
http://dx.doi.org/10.1080/15592294.2020.1817290