Cargando…

Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels

Epigenetic architecture is influenced by genetic and environmental factors, but little is known about their relative contributions or longitudinal dynamics. Here, we studied DNA methylation (DNAm) at over 750,000 CpG sites in mononuclear blood cells collected at birth and age 7 from 196 children of...

Descripción completa

Detalles Bibliográficos
Autores principales:	McKennan, Chris, Naughton, Katherine, Stanhope, Catherine, Kattan, Meyer, O’Connor, George T., Sandel, Megan T., Visness, Cynthia M., Wood, Robert A., Bacharier, Leonard B., Beigelman, Avraham, Lovinsky-Desir, Stephanie, Togias, Alkis, Gern, James E., Nicolae, Dan, Ober, Carole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143220/ https://www.ncbi.nlm.nih.gov/pubmed/32997571 http://dx.doi.org/10.1080/15592294.2020.1817290

Ejemplares similares

Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2
por: Jackson, Daniel J., et al.
Publicado: (2020)

The Balance of Weak and Strong Interactions in Genetic Networks
por: Poyatos, Juan F.
Publicado: (2011)

Associations between outdoor air pollutants and non-viral asthma exacerbations and airway inflammatory responses in children and adolescents living in urban areas in the USA: a retrospective secondary analysis
por: Altman, Matthew C, et al.
Publicado: (2023)

Applied statistical mechanics : thermodynamic and transport properties of fluids
por: Reed, Thomas M. (Thomas McKennan)
Publicado: (1973)

Reply
por: Jackson, Daniel J., et al.
Publicado: (2020)

Comparison of the Etiology of Viral Respiratory Illnesses in Inner-City and Suburban Infants
por: Gern, James E., et al.
Publicado: (2012)

Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children
por: Altman, Matthew C., et al.
Publicado: (2019)

Association of the Infant Gut Microbiome With Early Childhood Neurodevelopmental Outcomes: An Ancillary Study to the VDAART Randomized Clinical Trial
por: Sordillo, Joanne E., et al.
Publicado: (2019)

Applying Lessons from the COVID-19 Pandemic to Improve Pediatric Asthma Care
por: Lovinsky-Desir, Stephanie, et al.
Publicado: (2022)

scMD: cell type deconvolution using single-cell DNA methylation references
por: Cai, Manqi, et al.
Publicado: (2023)

Development of a Rhinovirus Inoculum Using a Reverse Genetics Approach
por: Gern, James E, et al.
Publicado: (2019)

The relationship of school performance with self-control and grit is strongly genetic and weakly causal
por: Kevenaar, Sofieke T., et al.
Publicado: (2023)

The Strong and the Weak
por: Stafford-Clark, David
Publicado: (1964)

The influence of atopy and asthma on immune responses in inner‐city adults
por: Kakumanu, Sujani, et al.
Publicado: (2016)

Host genetic variation in mucosal immunity pathways influences the upper airway microbiome
por: Igartua, Catherine, et al.
Publicado: (2017)

Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus
por: Soliai, Marcus M., et al.
Publicado: (2021)

Acute chest syndrome, airway inflammation and lung function in sickle cell disease
por: De, Aliva, et al.
Publicado: (2023)

The Urban Environment and Childhood Asthma (URECA) birth cohort study: design, methods, and study population
por: Gern, James E, et al.
Publicado: (2009)

Weak genetic structure despite strong genomic signal in lesser sandeel in the North Sea
por: Jiménez‐Mena, Belén, et al.
Publicado: (2019)

Accurate estimation of rare cell type fractions from tissue omics data via hierarchical deconvolution
por: Huang, Penghui, et al.
Publicado: (2023)

Measurement of intraindividual airway tone heterogeneity and its importance in asthma
por: Brown, Robert H., et al.
Publicado: (2016)

Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region
por: Clay, Selene M., et al.
Publicado: (2022)

Are the weak interactions strong?
por: Abbott, Laurence F, et al.
Publicado: (1981)

Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings
por: Dapas, Matthew, et al.
Publicado: (2023)

The Children’s Respiratory and Environmental Workgroup (CREW) birth cohort consortium: design, methods, and study population
por: Gern, James E., et al.
Publicado: (2019)

Association of citrulline concentration at birth with lower respiratory tract infection in infancy: Findings from a multi-site birth cohort study
por: Snyder, Brittney M., et al.
Publicado: (2022)

Gut Microbiota and Overweight in 3-year Old Children
por: Karvonen, Anne M., et al.
Publicado: (2018)

Chaos, weak and strong turbulence
por: Procaccia, Itamar
Publicado: (1990)

The strong electromagnetic and weak couplings
por: Llewellyn Smith, Christopher Hubert
Publicado: (1983)

Strong force - Weak force
Publicado: (1991)

Strong and weak CP violation
por: Ellis, Jonathan Richard, et al.
Publicado: (1979)

Orbits in weak and strong bars
por: Contopoulos, George, et al.
Publicado: (1980)

The Structural and Social Determinants of the Racial/Ethnic Disparities in the U.S. COVID-19 Pandemic. What’s Our Role?
por: Thakur, Neeta, et al.
Publicado: (2020)

DNA methylation of the allergy regulatory gene interferon gamma varies by age, sex, and tissue type in asthmatics
por: Lovinsky-Desir, Stephanie, et al.
Publicado: (2014)

African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans
por: Washington, Charles, et al.
Publicado: (2022)

Gravitational Lensing: Strong, Weak and Micro
por: Schneider, Peter, et al.
Publicado: (2006)

Relativistic rapprochement of weak and strong interactions
por: Streltsov, V N
Publicado: (1995)

Weak-strong duality and the modular group
por: Zaganescu, M
Publicado: (1995)

On symmetries shared by strong and weak interactions
por: Pais, A
Publicado: (1960)

Strong and weak CP violation at LEAR
por: Gabathuler, Erwin, et al.
Publicado: (1982)

Cannot write session to /tmp/vufind_sessions/sess_3fip7j1difh0euqhlhh5t4bcac