Effects of Magnesium, Calcium, and Aluminum Chelation on Fluoroquinolone Absorption Rate and Bioavailability: A Computational Study

Fluoroquinolones (FQs) are a widespread class of broad-spectrum antibiotics prescribed as a first line of defense, and, in some cases, as the only treatment against bacterial infection. However, when administered orally, reduced absorption and bioavailability can occur due to chelation in the gastro...

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Detalles Bibliográficos
Autores principales: Walden, Daniel M., Khotimchenko, Maksim, Hou, Hypatia, Chakravarty, Kaushik, Varshney, Jyotika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143323/
https://www.ncbi.nlm.nih.gov/pubmed/33919271
http://dx.doi.org/10.3390/pharmaceutics13050594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143323/
https://www.ncbi.nlm.nih.gov/pubmed/33919271
http://dx.doi.org/10.3390/pharmaceutics13050594

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