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Mechanism of Resistance Development in E. coli against TCAT, a Trimethoprim-Based Photoswitchable Antibiotic

During the last decades, a continuous rise of multi-drug resistant pathogens has threatened antibiotic efficacy. To tackle this key challenge, novel antimicrobial therapies are needed with increased specificity for the site of infection. Photopharmacology could enable such specificity by allowing fo...

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Detalles Bibliográficos
Autores principales: Lauxen, Anna I., Kobauri, Piermichele, Wegener, Michael, Hansen, Mickel J., Galenkamp, Nicole S., Maglia, Giovanni, Szymanski, Wiktor, Feringa, Ben L., Kuipers, Oscar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143356/
https://www.ncbi.nlm.nih.gov/pubmed/33919397
http://dx.doi.org/10.3390/ph14050392