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Mechanism of Resistance Development in E. coli against TCAT, a Trimethoprim-Based Photoswitchable Antibiotic
During the last decades, a continuous rise of multi-drug resistant pathogens has threatened antibiotic efficacy. To tackle this key challenge, novel antimicrobial therapies are needed with increased specificity for the site of infection. Photopharmacology could enable such specificity by allowing fo...
Autores principales: | Lauxen, Anna I., Kobauri, Piermichele, Wegener, Michael, Hansen, Mickel J., Galenkamp, Nicole S., Maglia, Giovanni, Szymanski, Wiktor, Feringa, Ben L., Kuipers, Oscar P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143356/ https://www.ncbi.nlm.nih.gov/pubmed/33919397 http://dx.doi.org/10.3390/ph14050392 |
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