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Photodynamic Therapy as an Oxidative Anti-Tumor Modality: Negative Effects of Nitric Oxide on Treatment Efficacy

Anti-tumor photodynamic therapy (PDT) is a unique oxidative stress-based modality that has proven highly effective on a variety of solid malignancies. PDT is minimally invasive and generates cytotoxic oxidants such as singlet molecular oxygen ((1)O(2)). With high tumor site-specificity and limited o...

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Detalles Bibliográficos
Autores principales: Girotti, Albert W., Fahey, Jonathan M., Korbelik, Mladen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143374/
https://www.ncbi.nlm.nih.gov/pubmed/33919266
http://dx.doi.org/10.3390/pharmaceutics13050593